| South Africa |
| 30 |
| South America |
| 16 |
| 25 October 1980 | ||||||
| Prince of Wales Country Club, Santiago | ||||||
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| Captain: Morné du Plessis | Referee: LM Prideaux (France) | |||||
| Coach: Nelie Smith | Attendance: 3700 | |||||
| Position | Player | Province | Age | Prev Tests | Scoring |
| Loose-head Prop | Richard Prentis | Tvl | 33 | 7 | |
| Hooker | Willie Kahts | N-Tvl | 33 | 4 | |
| Tight-head Prop | Martiens le Roux | OFS | 29 | 5 | |
| Lock | Moaner van Heerden | N-Tvl | 29 | 15 | |
| Lock | Louis Moolman | N-Tvl | 29 | 8 | |
| Flank | Rob Louw | WP | 25 | 7 | |
| Flank | Theuns Stofberg | N-Tvl | 25 | 10 | |
| Eighthman (C) | Morné du Plessis | WP | 31 | 20 | 1 try |
| Scrumhalf | Divan Serfontein | WP | 26 | 5 | |
| Flyhalf | Naas Botha | N-Tvl | 22 | 7 | 3 conversions |
| Left Wing | Gerrie Germishuys | Tvl | 30 | 13 | 2 tries |
| Inside Centre | Willie du Plessis | WP | 25 | 7 | |
| Outside Centre | Danie Gerber | EP | 22 | 1 | 1 try |
| Right Wing | Ray Mordt | Rhodesia | 23 | 7 | 2 tries |
| Full Back | Gysie Pienaar | OFS | 25 | 6 |
| South America: 2 tries, 1 conversion, 1 penalty, 1 dropgoal |