| South Africa |
| 17 |
| England |
| 25 |
| 2 December 2000 | ||||||
| Twickenham, London | ||||||
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| Captain: André Vos | Referee: Dave McHugh (Ireland) | |||||
| Coach: Harry Viljoen | Attendance: 75000 | |||||
| Position | Player | Province | Age | Prev Tests | Scoring |
| Loose-head Prop | Robbie Kempson | WP | 26 | 24 | |
| Hooker | John Smit | Sharks | 22 | 9 | |
| Tight-head Prop | Willie Meyer | Lions | 33 | 11 | |
| Lock | Albert van den Berg | Sharks | 26 | 18 | |
| Lock | Mark Andrews | Sharks | 28 | 67 | |
| Flank | Corné Krige | WP | 25 | 14 | |
| Flank | André Venter | Cheetahs | 30 | 55 | |
| Eighthman (C) | André Vos | Lions | 25 | 21 | |
| Scrumhalf | Joost van der Westhuizen | Blue Bulls | 29 | 67 | |
| Flyhalf | Braam van Straaten | WP | 29 | 14 | 1 try, 4 penalties |
| Left Wing | Stefan Terblanche | Sharks | 25 | 21 | |
| Inside Centre | Japie Mulder | Lions | 31 | 31 | |
| Outside Centre | Robbie Fleck | WP | 25 | 22 | |
| Right Wing | Breyton Paulse | WP | 24 | 18 | |
| Full Back | Percy Montgomery | WP | 26 | 43 | |
| Reserve | Grant Esterhuizen | Lions | 24 | 6 | |
| Reserve | AJ Venter | Sharks | 27 | 1 | |
| Reserve | Ollie le Roux | Sharks | 27 | 35 | |
| Reserve | Dan van Zyl | WP | 29 | 0 | |
| Reserve | Warren Brosnihan | Sharks | 28 | 5 |
| England: 1 try, 1 conversion, 6 penalties |